Dr. Wiltshire is the Associate Director of the UPMC Cytogenetics Laboratories.
Clinical Expertise
Clinical Cytogenetics and Genomics
Certifications and Licensures
American Board of Medical Genetics and Genomics Certification
Certificate of Qualification, New York State Department of Health
Laboratory Director License, New Jersey State Board of Medical Examiners
Specialties
Cancer Cytogenetics and Molecular Genomics
Dr. Wiltshire’s research interest includes cultivating innovative cytogenetic, molecular genomic, and bioinformatics applications to improve detection of genetic biomarkers to help elucidate functional pathways for genetic diseases and disorders, with a special interest in neurological disorders and malignancies.
McLendon, R.E., Herndon II, J.E., West, B., Reardon, D., Wiltshire, R., Ahmed Rasheed, B.K., Quinn, J., Friedman, H.S., Friedman, A.H., Bigner, D.D. Survival Analysis of Presumptive Prognostic Markers among Oligodendrogliomas. Cancer. 104(8):1693-1699, 2005.
Wiltshire, R. N., Herndon II, J.E., Lloyd, A., Friedman, H. S., Bigner, D. D., Bigner, S.H., and McLendon, R. E. Comparative genomic hybridization analysis of astrocytoma: prognostic and diagnostic implications. The Journal of Molecular Diagnostics 6: 166-179, 2004.
McLendon R.E., Rasheed A., Wiltshire R., and Herndon J. Correlation of 1p-19q-defects in human gliomas with the light microscopic appearance of oligodendroglioma. Modern Pathology 17: 604-605, 2004.
Heimberger, A.B., Wiltshire, R.N., Bronec, P., Cummings, T.J., and McLendon, R.E. Biphasic malignant meningioma: A comparative genomic hybridization study. Clinical Neuropathology 21: 258-264, 2002.
Aldosari, N., Wiltshire, R. N., Dutra, D., Schrock, E., McLendon, R. E., Friedman, H. S., Bigner, D. D., and Bigner, S. H. Comprehensive molecular cytogenetic investigation of chromosomal abnormalities in human medulloblastoma cell lines and xenograft. Neuro-Oncology 4: 75-85, 2002.
Wiltshire, R.N., Dennis, T., Sondak, V. K., Meltzer, P.S., and Trent, J.M. Application of molecular cytogenetic techniques in the case study of a human cutaneous metastatic melanoma. Cancer Genetics Cytogenetics 131: 97- 103, 2001.
Wiltshire, R. N., Ahmed Rasheed, B. K., Friedman, H. S., Friedman, A. H., and Bigner, S. H. Comparative genetic patterns of glioblastoma multiforme: potential diagnostic tool for tumor classification. Neuro-Oncology 2: 164-173, 2000.